Psychological Research in Fibromyalgia and Chronic Pain (ÀGORA Group)

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Parc Sanitari Sant Joan de Déu

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Our group conducts patient-centred research, which is invaluable insofar as it can be translated into clinical practice. Our main focus is on the economic evaluation of psychological and pharmacological treatments for fibromyalgia and chronic pain, on the neurobiological basis of chronic pain and on psychometric aspects of the measures usually administered to these patients.

More specifically, the ÀGORA Group is interested in studying which treatments are effective and cost-effective for patients with chronic pain, identifying the specific patient profile (clusters) in which these treatments are most effective and how they act cognitively, emotionally and physiologically.

Several of our members, including the group leader, belong to the Network for Research in Preventive Activities and Health Promotion in Primary Care (ISCIII; RD16/0007/0012) and the group is recognised and receives funding as an emerging group from AGAUR (Government of Catalonia; 2017 SGR 667).

Research lines

  1. Evaluation of the effectiveness and cost-effectiveness of different psychological and pharmacological treatments for the management of fibromyalgia and chronic pain.
  2. Analysis of the role of neuroimaging variables (structural, functional, perfusion and spectroscopy) and inflammatory variables (pro- and anti-inflammatory cytokines) in predicting responses to the treatments under evaluation.
  3. Development and psychometric validation of patient-reported outcomes (PRO).
  4. Mindfulness, health and quality of life. This line of psychosocial research aims to assess the therapeutic potential of community activities (effect of the Camino de Santiago on mental health and quality of life; assessing well-being associated with implementation of a green roof system in homes for the elderly).

Scientific objectives

  1. To analyse the efficiency of third-generation psychological treatments and innovative pharmacological treatments for patients with chronic pain.
  2. To develop and validate "psychological process variables" and pinpoint which psychological constructs are involved in the response to treatment.
  3. To analyse the brain from a structural and functional point of view concerning the areas that predict the response to treatments as well as those likely to undergo changes as a result of the therapy.
  4. To analyse the role of psychoneuroimmunological variables in the prediction and mediation of treatment outcomes.

Area/Field of expertise

The research carried out by the group is part of the study of the clinical, economic, psychobiological and social aspects of diseases with chronic non-malignant pain, especially musculoskeletal pain. The main objective is to study the cost-effectiveness of pain control therapy and the role of psychological, biological and social variables that act as predictors and/or mediators of therapeutic change. The methodology generally employed is the conduct of randomised controlled clinical trials, although we also have experience in meta-analysis and psychometric assessment.

With the aim of conducting successful research in fibromyalgia and chronic pain, we have a multidisciplinary team (five psychologists -one also a health biologist-, a statistician, a rheumatologist, an anaesthetist and a GP) made up of researchers and professionals from Sant Joan de Déu Health Park  and other academic or clinical institutions in our territory.

In recent years and in various different projects, we have evaluated the effectiveness and cost-effectiveness of different pharmacological and non-pharmacological treatments for fibromyalgia and major depression, thanks primarily to yearly funding from ISCIII. Our group is defined as a "dry lab" that seeks to contribute significantly to knowledge about the neurobiological mechanisms underlying the effects of therapies for chronic pain.

Group members

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Projects

Project name:
Efectividad y coste-utilidad de la terapia cognitiva basada en mindfulness (MBCT) para prevenir la recaída o recurrencia depresiva en adultos españoles con trastorno depresivo recurrente: un ensayo controlado aleatorizado (estudio Bounce-Back from Depress
Leader
Jesús Montero Marin
Funding entities:
Instituto de Salud Carlos III (ISCIII)
Code
PI23/00021
Starting - finishing date:
2024 - 2026
Project name:
Coste-utilidad y efectos fisiológicos de una aplicación digital para pacientes con fibromialgia basada en la Terapia de Aceptación y Compromiso (Proyecto SMART-FM-Spain)
Leader
Juan Vicente Luciano Devis
Funding entities:
Luciano Devis, Juan Vicente, Instituto de Salud Carlos III (ISCIII), Fundació Privada per a la Recerca i la Docència Sant Joan de Déu - FSJD
Code
PI22/00829
Starting - finishing date:
2023 - 2025
Project name:
Análisis de procesos en la terapia cognitiva basada en la atención plena (MBCT) para la prevención de la recaída depresiva en el estudio controlado aleatorizado PREVENT
Leader
Jesús Montero Marin
Funding entities:
Ministerio De Universidades
Code
CAS22/00436
Starting - finishing date:
2023 - 2024
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Theses

  • Evaluación clínica y económica de la Terapia de Aceptación y Compromiso y de la Terapia de Activación Conductual en pacientes con dolor lumbar crónico y síntomas de depresión
    Author
    Sanabria Mazo, Juan Pablo
    Institution
    UNIVERSIDAD AUTÓNOMA DE BARCELONA
    23/02/2024
  • Caracterització del perfil immunoinflamatori i efectes del mindfulness en pacients amb fibromiàlgia
    Author
    Andrés Rodríguez, Laura
    Institution
    UNIVERSIDAD AUTÓNOMA DE BARCELONA
    22/07/2020
  • Identificación de subtipos de pacientes con fibromialgia y análisis de la eficacia y coste-utilidad del programa de reducción del estrés basado en mindfulness
    Author
    Pérez Aranda, Adrián
    Institution
    UNIVERSIDAD DE BARCELONA
    18/02/2020
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