José Carlos Jiménez Chillarón
Jefe de Grupo Senior
Research group
The researcher Josep C. Jiménez Chillarón graduated in Biology in 1992 from the University of Barcelona and received his Doctor of Biology (Biochemistry and Molecular Biology) degree from the University of Barcelona in 2000.
From 2000 to 2005 he held a postdoctoral stay at the Joslin Diabetes Center-Harvard Medical School, Boston, USA. He studied, through experimental models, the molecular mechanisms involved in the development of obesity and diabetes associated with low birth weight.
From 2005 to 2007 she was Instructor in Pediatrics-Harvard Medical School at Children's Hospital Boston, Endocrine Division, USA. He studied the role of the epigenome in the development of obesity-diabetes in response to nutrition during pregnancy and lactation.
In 2007, he joined the Sant Joan de Déu Foundation as a Researcher, within the Endocrinology Service of the SJD Barcelona Children’s Hospital.
She is currently leading, in conjunction with Dr. Carles Lerin, the research group on Pediatric Metabolic Diseases · Institut de Recerca Sant Joan de Déu. Within the research group, it is IP of 2 lines of research:
1. Childhood obesity: Murine models.
2. Development of new treatments for type 1 diabetes.
SJD Barcelona Children's Hospital Last Publications
- Parra-Vargas, M, Bouret, SG, Bruning, JC, de Moura, EG, Garland, T, Lisboa, PC, Ozanne, SE, Patti, ME, Plagemann, A, Speakman, JR, Tena-Sempere, M, Vergely, C, Zeltser, LM and Jimenez-Chillaron JC The long-lasting shadow of litter size in rodents: litter size is an underreported variable that strongly determines adult physiology molecular metabolism . 71: .
- Ribas-Aulinas, F, Ribó-Gené S, Casas, E, Mourin-Fernández M, Ramon-Krauel M, Díaz-Naderi R, Lerin C, Kalko, SG, Vavouri, T and Jimenez-Chillaron JC Intergenerational Inheritance of Hepatic Steatosis in a Mouse Model of Childhood Obesity: Potential Involvement of Germ-Line microRNAs Nutrients . 15(5): .
- Molina-Giraldo PX, Murillo-Garcia S, Meis L, Sans-Capdevila O, Amat-Bou M, Llobet-Garcès M, Jimenez-Chillaron JC, Ramon-Krauel M and Lerin C A time-restricted feeding intervention in children and adolescents with obesity: The TRansForm study protocol Frontiers in Nutrition . 9: 1026694-1026694.
Projects
- Project name:
- SGR 2022-2024_Malaties metabòliques d'origen pediàtric
- Leader
- Carles Lerin Martinez
- Funding entities:
- Agaur - Agència de Gestió d'Ajuts Universitaris i de Recerca
- Code
- 2021 SGR 00661
- Starting - finishing date:
- 2022 - 2024
- Project name:
- Non-genomic Inheritance of environmentally-induced traits: Deciphering epigenetically-driven genetic variation in mammals
- Leader
- José Carlos Jiménez Chillarón
- Funding entities:
- John Templenton Foundation
- Code
- ID 62167
- Starting - finishing date:
- 2021 - 2024
- Project name:
- Obesidad infantil: La bola de nieve que precede la avalancha metabólica (una aproximación epigenómica)
- Leader
- José Carlos Jiménez Chillarón
- Funding entities:
- Fundación Salud 2000 (Merck Salud)
- Code
- PCP00284
- Starting - finishing date:
- 2020 - 2022
News
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IRSJD researchers have discovered an intergenerational inheritance mechanism in mouse models of childhood obesity
A study led by Dr. Josep Jiménez-Chillaron, a researcher at the Institut de Recerca Sant Joan de Déu and the University of Barcelona, suggests that hepatic steatosis could be intergenerationally inherited through paternal germ line microRNAs. Hepatic steatosis is a condition that is associated with childhood obesity. The results of this study have been published in the scientific journal Nutrients.
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First scientific conference on nanotechnology and rare diseases
The Spanish nanomedicine platform (Nanomed Spain), together with the Sant Joan de Déu Research Institute and the IBEC (Institute of Bioengineering of Catalonia), organised an event within the framework of the Rare Disease Day at which they presented the latest innovations in the field of nanomedicine for the treatment and diagnosis of these diseases.