Core Facilities

Unit of Desing, Analysis and Interpretation of Omic data

The Unit of Desing, Analysis and Interpretation of Omic data (DAI-Omics) provides expert support and individualised assistance for the design, analysis and interpretation of genomic studies conducted in the field of biomedical translational research. The DAI-Omics Unit integrates expertise in the field of genomics and bioinformatics with experience and knowledge of the genetic bases and the clinical context of human pathologies.

The DAI-Omics Unit provides support for researchers at the Institut de Recerca Sant Joan de Déu Barcelona and Hospital Sant Joan de Déu, as well as external institutions.

The DAI-Omics Unit provides a comprehensive service that includes:

  • Consultancy for experimental Design

    with Genomic Advice of genomic studies, focused on the research plan and objectives, taking into account samples resources, suitable genomic platforms (technology) and cost effective approaches.
  • Omics Data Analysis (Big Data)

    by means of annotated data, optimized bioinformatics pipeline and web-based tools specific for each type of data.
  • Interpretation and integration

    of results with clinical and biological data in the context of the research plan and scientific knowledge.

The DAI-Omics Unit also provides assistance for the preparation and deposit of databases for at public genomic data repositories.

Main functions

  • Design
    • Define objectives and research plan
    • Samples (Cohort, type and references)
    • Experimental design
    • Adequate platform / technology
  • Analysis
    • Optimised pipeline: quality control, normalization and filtering
    • Data processing and analysis
    • Functional genomics analysis
    • Data mining
  • Interpretation
    • Personalized analyses
    • UCSC Genome Browser settings
    • Comparison with public databases
    • Support for writing related sections of manuscripts
    • Preparation and deposit of datasets at public genomic data repositories