Unit of Desing, Analysis and Interpretation of Omic data

The Unit of Desing, Analysis and Interpretation of Omic data (DAI-Omics) provides expert support and individualised assistance for the design, analysis and interpretation of genomic studies conducted in the field of biomedical translational research. The DAI-Omics Unit integrates expertise in the field of genomics and bioinformatics with experience and knowledge of the genetic bases and the clinical context of human pathologies.

The DAI-Omics Unit provides support for researchers at the Institut de Recerca Sant Joan de Déu Barcelona and Hospital Sant Joan de Déu, as well as external institutions.

The DAI-Omics Unit provides a comprehensive service that includes:

• Consultancy for experimental Design

  with Genomic Advice of genomic studies, focused on the research plan and objectives, taking into account samples resources, suitable genomic platforms (technology) and cost effective approaches.

• Omics Data Analysis (Big Data)

  by means of annotated data, optimized bioinformatics pipeline and web-based tools specific for each type of data.

• Interpretation and integration

  of results with clinical and biological data in the context of the research plan and scientific knowledge.

Main functions

• Design
  • Define objectives and research plan
  • Samples (Cohort, type and references)
  • Experimental design
  • Adequate platform / technology
• Analysis
  • Optimised pipeline: quality control, normalization and filtering
  • Data processing and analysis
  • Functional genomics analysis
  • Data mining
• Interpretation
  • Personalized analyses
  • UCSC Genome Browser settings
  • Comparison with public databases
  • Support for writing related sections of manuscripts
  • Preparation and deposit of datasets at public genomic data repositories