People / Staff

Carles Lerin Martinez

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Publications

  • Pihlajamäki J, Lerin C, Itkonen P, Boes T, Floss T, Schroeder J, Dearie F, Crunkhorn S, Burak F, Jimenez-Chillaron JC, Kuulasmaa T, Miettinen P, Park PJ, Nasser I, Zhao Z, Zhang Z, Xu Y, Wurst W, Ren H, Morris AJ, Stamm S, Goldfine AB, Laakso M and Patti ME.

    Expression of the Splicing Factor Gene SFRS10 Is Reduced in Human Obesity and Contributes to Enhanced Lipogenesis

    CELL METABOLISM . 14(2): 208-218. Number of citations: 123

    [doi:10.1016/j.cmet.2011.06.007]

  • Kelly TJ, Lerin C, Haas W, Gygi SP and Puigserver P.

    GCN5-mediated Transcriptional Control of the Metabolic Coactivator PGC-1 beta through Lysine Acetylation

    JOURNAL OF BIOLOGICAL CHEMISTRY . 284(30): 19945-19952. Number of citations: 98

    [doi:10.1074/jbc.M109.015164]

  • Montori-Grau M, Minor R, Lerin C, Allard J, Garcia-Martinez C, de Cabo R and Gómez-Foix AM.

    Effects of aging and calorie restriction on rat skeletal muscle glycogen synthase and glycogen phosphorylase

    EXPERIMENTAL GERONTOLOGY . 44(6-7): 426-433. Number of citations: 15

    [doi:10.1016/j.exger.2009.03.005]

  • Coste A, Louet JF, Lagouge M, Lerin C, Antal MC, Meziane H, Schoonjans K, Puigserver P, O'Malley BW and Auwerx J.

    The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1 alpha

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA . 105(44): 17187-17192. Number of citations: 156

    [doi:10.1073/pnas.0808207105]

  • Rodgers JT, Lerin C, Gerhart-Hines Z and Puigserver P.

    Metabolic adaptations through the PGC-1 alpha and SIRT1 pathways

    FEBS LETTERS . 582(1): 46-53. Number of citations: 474

    [doi:10.1016/j.febslet.2007.11.034]

  • Montori-Grau M, Guitart M, Lerin C, Andreu AL, Newgard CB, García-Martínez C and Gómez-Foix AM.

    Expression and glycogenic effect of glycogen-targeting protein phosphatase 1 regulatory subunit G(L) in cultured human muscle

    BIOCHEMICAL JOURNAL . 405: 107-113. Number of citations: 21

    [doi:10.1042/BJ20061572]

  • Gerhart-Hines Z, Rodgers JT, Bare O, Lerin C, Kim SH, Mostoslavsky R, Alt FW, Wu Z and Puigserver P.

    Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1 alpha

    EMBO JOURNAL . 26(7): 1913-1923. Number of citations: 1002

    [doi:10.1038/sj.emboj.7601633]

  • Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, Messadeq N, Milne J, Lambert P, Elliott P, Geny B, Laakso M, Puigserver P and Auwerx J.

    Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1 alpha

    Cell . 127(6): 1109-1122. Number of citations: 3224

    [doi:10.1016/j.cell.2006.11.013]

  • Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW, Spencer RG, Lakatta EG, Le Couteur D, Shaw RJ, Navas P, Puigserver P, Ingram DK, de Cabo R and Sinclair DA.

    Resveratrol improves health and survival of mice on a high-calorie diet

    Nature . 444(7117): 337-342. Number of citations: 3442

    [doi:10.1038/nature05354]

  • Lerin C, Rodgers JT, Kalume DE, Kim SH, Pandey A and Puigserver P.

    GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1 alpha

    CELL METABOLISM . 3(6): 429-438. Number of citations: 332

    [doi:10.1016/j.cmet.2006.04.013]