
Laia Alsina Manrique de Lara
Jefe de Grupo
Research group
Researcher Laia Alsina graduated in Medicine in 2000 from the University of Barcelona, and he obtained a specialization in Paediatrics in 2004 at the Hospital San Juan de Dios Barcelona. She obtained her PhD degree from the University of Barcelona, in 2008.
Between 2008 and 2010 he completed a postdoctoral stay at the Baylor Institute for Immunology Research in Dallas, where he studied the immune pathways related to primary immunodeficiencies.
In 2018, she was appointed Head of the Unit of Clinical Immunology and Primary Immunodeficiencies of the SJD Barcelona Children's Hospital and coordinated the Unit of Clinical Immunology between the Clinical Hospital and Sant Joan de Déu.
She is an Associate Professor at the University of Barcelona, since 2018.
She currently co-leads the Study Group of Diseases for Immune Dysfunction in Paediatrics (GEMDIP) where he studies the pathways affected in different forms of primary immunodeficiency, and how to apply this knowledge in personalized therapies in patients with diseases due to immune dysfunction, as well as the impact on the childhood immune system of various immunosuppressive therapies.
Professional network profiles
Related websites
Last Publications
- Berrueco R, González E, Deyà-Martinez A, Solsona M, García-García AP, Calzada-Hernández J, Luo Y, Vlagea A, Ruiz-Llobet A and Alsina L Mycophenolate mofetil for autoimmune cytopenias in children: high rates of response in inborn errors of immunity Frontiers in pediatrics . 11: 1174671-1174671.
- Armangue-Salvador T, Olivé-Cirera G, Martínez-Hernandez E, Rodes M, Peris-Sempere V, Guasp M, Ruiz R, Palou E, González A, Marcos MÁ, Erro ME, Bataller L, Corral-Corral Í, Planagumà J, Caballero E, Vlagea A, Chen J, Bastard P, Materna M, Marchal A, Abel L, Cobat A, Alsina L, Fortuny-Guasch C, Saiz A, Mignot E, Vanderver A, Casanova JL, Zhang SY and Dalmau J Neurologic complications in herpes simplex encephalitis: clinical, immunological and genetic studies. BRAIN . 146(10): 4306-4319.
- Block J, Rashkova C, Castanon I, Zoghi S, Platon J, Ardy RC, Fujiwara M, Chaves B, Schoppmeyer R, van der Made CI, Jimenez Heredia R, Harms FL, Alavi S, Alsina L, Sanchez Moreno P, Ávila Polo R, Cabrera-Pérez R, Kostel Bal S, Pfajfer L, Ransmayr B, Mautner AK, Kondo R, Tinnacher A, Caldera M, Schuster M, Domínguez Conde C, Platzer R, Salzer E, Boyer T, Brunner HG, Nooitgedagt-Frons JE, Iglesias-Jimenez E, Deyà-Martinez A, Camacho-Lovillo M, Menche J, Bock C, Huppa JB, Pickl WF, Distel M, Yoder JA, Traver D, Engelhardt KR, Linden T, Kager L, Hannich JT, Hoischen A, Hambleton S, Illsinger S, Da Costa L, Kutsche K, Chavoshzadeh Z, van Buul JD, Anton-Lopez J, Calzada-Hernández J, Neth O, Viaud J, Nishikimi A, Dupré L and Boztug K Systemic Inflammation and Normocytic Anemia in DOCK11 Deficiency. NEW ENGLAND JOURNAL OF MEDICINE . 389(6): 527-539.
Projects
- Project name:
- Functional profiling array for primary immune regulatory disorders-research
- Leader
- Laia Alsina Manrique de Lara
- Funding entities:
- Pharming Group N.V.
- Code
- PCP00389
- Starting - finishing date:
- 2023 - 2025
- Project name:
- Estudio multicéntrico fase 2 en pacientes pediátricos (0-18 años) con leucmeia linfoblástica aguda B CD19+ en recaída o refractaria
- Leader
- Susana Rives Solà
- Funding entities:
- Instituto de Salud Carlos III (ISCIII)
- Code
- ICI21/00033
- Starting - finishing date:
- 2022 - 2025
- Project name:
- Caracterización de las alteraciones inmunológicas, específicamente en células Treg, implicadas en la desregulación inmune en pacientes pediátricos con errores innatos de inmunidad,hacia terapias dirigidas
- Leader
- Laia Alsina Manrique de Lara
- Funding entities:
- Instituto de Salud Carlos III (ISCIII)
- Code
- PI21/00211
- Starting - finishing date:
- 2022 - 2024
News
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Mutation in DOCK11 gene explains rare disorder in immune system regulation
Researchers from the Institut de Recerca Sant Joan de Déu - SJD Barcelona Children's Hospital participate in an international study, published in the prestigious scientific journal New England Journal of Medicine, which describes for the first time a new disease of the immune system caused by a mutation of the DOCK11 gene.
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Researchers discover a key factor that predicts COVID-19 disease severity
A study led by Drs. Laia Alsina and Iolanda Jordan from the IRSJD evidences a key factor that predicts the severity of COVID-19: an alteration of the first immune response to SARS-CoV-2 infection, in key molecules in the anti-infective response. The study has been published in open access in the journal iScience.
More activities
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Defensa tesi doctoral: Ana Pilar García García
Auditori Plaza, Hospital Sant Joan de Déu · Online