Clinical groups and innovation
Research Program
Leaders
Where we are
Parc Sanitari Sant Joan de Déu
"Clinical Groups and Innovation" is a heterogeneous group comprising various medical specialties and nursing professionals, aiming to contribute through clinical research and applied innovation in healthcare. Its focus includes studying the epidemiology of prevalent diseases, their pathophysiology, optimizing treatments, and developing or implementing new devices and platforms powered by artificial intelligence to enhance clinical practice and medical treatment. Currently, our team is recognized as an SGR research group in the emerging category (File number and grant acceptance: 2021 SGR 01389).
Research lines
- Clinical and epidemiological research in neurology. PI: Dr. Nuria Berrocal.
- Ethics research. PI: Bernabé Robles.
- Rehabilitation research. PI: Raffaele Fiorillo.
- Clinical and epidemiological research in emerging respiratory disease processes. PI: Rosana Hernando.
- Clinical research in aging. PI: Luis Lores.
- Research in general and digestive surgery. PI: Jordi Comajuncosas.
- Research in chronic musculoskeletal diseases. PI: Dr. Pilar Santos.
- Research in digestive system diseases. PI: Dr. Sandra Torra.
- Nursing research in chronic wounds. PI: Mr. Pere Coca.
- Research in allergic diseases. PI: Karolina Esponda Juárez.
- Innovation Unit (supporting different specialties). PI: Iñigo Chivite.
Scientific objectives
- In the field of neurology, the aim is to continue the studies already initiated in Alzheimer's and Parkinson's disease: the Analysis of Alzheimer's progression through data collected from medical records, the voice analysis project in patients with Parkinson's disease ("Voice loudness and auditory-sensory feedback in Parkinsonian voice production"), and the continuation of the open Start-On study for monitoring patients with Parkinson's disease and motor fluctuations. The Cognivitra innovation project (COGNItive VIgality TRAining at home) is almost complete, developing solutions for cognitive and physical training for people at risk of developing cognitive decline.
- In terms of ethics research, work will continue on the ongoing research study on the quality of ethical evaluation of research projects.
- In terms of respiratory pathology research, our main objectives are to continue conducting multicenter clinical trials to evaluate the efficacy and safety of drugs in respiratory pathology. At the same time, the team will supervise and complete the study "Real-time monitoring of asthma patients and their exposure to air pollution using a digital clinical platform," initiated thanks to the support of the Innovation group, in collaboration with the artificial intelligence expert N-Vision, and with the UB as part of an Industrial Doctorate program.
- Within Rehabilitation research, the challenge is to continue with innovative healthcare projects and consolidate its position with the Clinical Trials Unit. Participation in various multicenter studies has consolidated this group's position as a researcher in innovation.
- In the area of clinical research on aging, the plan is to continue the project "Intervention for Continuity of Care for Frail Patients in Primary Care after Hospital Discharge (CC-FRAPH): Evaluation of Effectiveness and Cost-Effectiveness" and to initiate original studies on oropharyngeal dysphagia and continue collaboration with the FaceRehab project.
- Regarding research in pathology in digestive surgery, we will continue with the project "Randomized prospective study to evaluate the usefulness of placing a reinforcement mesh in patients at high risk of presenting with an eventration of the laparoscopic trocar orifice." We are also pending the start of a separate clinical trial in robotic surgery.
- In the area of research on chronic musculoskeletal diseases, the objective is to continue deepening research in the field of arthritis and spondyloarthritis, given the prevalence of these pathologies, by initiating separate studies in this field. Currently, the studies "REMAPA: a retrospective study aimed at creating a multicenter registry of IPAF or interstitial lung diseases with autoimmune diseases" and "Prevalence of osteoporosis and fractures in patients with axial spondyloarthrosis. Predictive value of FRAX" are underway.
- In research on digestive system diseases, the goal is to continue multicenter studies and initiate new ones.
- In chronic wound research, the goal is to promote nursing research in the field of wound care. Chronic and difficult-to-heal wounds. The main study being worked on, which will be part of the doctoral thesis of its author and group PI, is: "Analgesic efficacy and clinical safety of topical sevoflurane in the treatment of chronic wounds."
- A recent addition to our group is the line of research in allergic diseases with participation in the multicenter study "Creation of a database for the monitoring and follow-up of patients with LTP syndrome: Food allergy due to sensitization to lipid transport proteins (LTPs). Involved foods, diagnostic methods, therapeutic strategies, patient outcomes." An original study is also in preparation.
- The Innovation Unit, which supports our group, has established itself as a scientific challenge, in addition to offering support for the different specialties, to lead its own projects, produce scientific publications, and/or register industrial and intellectual property arising from innovation projects.
Area/Field of expertise
Our group includes specialists with extensive experience in general and digestive surgery, pulmonology, digestive pathology, neurology, rheumatology, allergies, rehabilitation, ethics, aging, and specialized nursing. We also have innovation experts who support the rest of the professionals in projects that require it. The main objective of our research revolves around patient well-being and improving their quality of life, as well as ensuring that the research is responsible and respectful of the patients involved. Thus, our research is primarily oriented toward the study of epidemiological and clinical aspects to improve the diagnosis and treatment of the most prevalent pathologies in each of our areas or medical specialties. To this end, we conduct studies on the pathophysiological aspects of different diseases, safety and efficacy studies of new pharmacological treatments, as well as healthcare innovation projects in different fields (currently in neurology, rehabilitation, surgery, and pulmonology) and the study of new surgical techniques
Group members
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Antonio Callen Soto
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Jefe de Grupo
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Investigador
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Investigador
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Investigador
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Investigador
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Pere Coca Alves
Investigador
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Investigador
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Investigador

Last Publications
- Bermudo G, Del Rio B, Vicens-Zygmunt V, Bordas-Martinez J, Hernández M, Valenzuela C, Laporta R, Rigual Bobillo J, Portillo K, Millán-Billi P, Balcells E, Badenes-Bonet D, Bolivar S, Rodríguez-Portal JA, López Ramirez C, Tomás L, Fernández de Roitegi K, Sellarés J, Castillo D, González J, Barril S, Gutiérrez-Rodríguez Y, Caballero P, Alarcon J, Peñafiel J, Sanz-Santos J, Blavia R, Cristina Caupena Auledas, Segovia P, Santos-Pérez S, Ferrer A, Badia MB, Hereu P, Fuentes M, Montes-Worboys A, Franquet T, Luburich P and Molina-Molina M Pirfenidone in post-COVID19 pulmonary fibrosis (FIBRO-COVID): a phase 2 randomized clinical trial. EUROPEAN RESPIRATORY JOURNAL . 65(4): .
- Brunet-Mas E, Selva A, Bas-Cutrina F, Brujats A, Caballol B, Font R, Gomez B, Gonzalez-Muñosa C, Busquets D, Monfort D, Vera DP, Maristany E, Cirera G, Torres G, Castro-Poceiro J, Lopez J, Gonzalez-Gonzalez L, Màrquez-Mosquera L, Gallach M, Esteve M, Tremosa G, Sandra Torra Alzina, Robles-Alonso V, Garcia-Iglesias P, Rodríguez-Lago I and Calvet X Asymptomatic Inflammatory Bowel Disease Diagnosed During Colorectal Cancer Population Screening in Catalonia: Characteristics and Natural History CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY . 16(2): .
Projects
- Project name:
- Eficacia analgésica y seguridad clínica de la aplicación tópica de sevoflurano en el tratamiento de heridas crónicas
- Leader
- Pere Coca Alves
- Funding entities:
- Parc Sanitari de Sant Joan de Déu -Serveis de Salut Mental
- Code
- AR202401
- Starting - finishing date:
- 2024 - 2025
- Project name:
- AISN: Integrating AI in Stroke Neurorehabilitation
- Leader
- Raffaele Fiorillo
- Funding entities:
- European Commission
- Code
- 101057655
- Starting - finishing date:
- 2022 - 2026
- Project name:
- SGR 2022-2024_Grups Clínics i Innovació
- Leader
- Rosana Hernando Salvador
- Funding entities:
- Agaur - Agència de Gestió d'Ajuts Universitaris i de Recerca
- Code
- 2021 SGR 01389
- Starting - finishing date:
- 2022 - 2025