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Publicacions

  • Mateo-Lozano S.

    Aprataxin Tumor Levels Predict Response of Colorectal Cancer Patients to Irinotecan-based Treatment

    CLINICAL CANCER RESEARCH . 16(8): 2375-2382. Nº de cites: 35

    [doi:10.1158/1078-0432.CCR-09-3275]

  • Tirado, OM, MacCarthy, CM, Fatima, N, Villar, J, Mateo-Lozano S and Notario, V.

    Caveolin-1 promotes resistance to chemotherapy-induced apoptosis in Ewing's sarcoma cells by modulating PKC alpha phosphorylation

    INTERNATIONAL JOURNAL OF CANCER . 126(2): 426-436. Nº de cites: 43

    [doi:10.1002/ijc.24754]

  • Mateo-Lozano S.

    The Receptor Tyrosine Kinase EPHB4 Has Tumor Suppressor Activities in Intestinal Tumorigenesis

    CANCER RESEARCH . 69(18): 7430-7438. Nº de cites: 55

    [doi:10.1158/0008-5472.CAN-09-0706]

  • Mateo-Lozano S.

    Pyrazolo[1,5-a]-1,3,5-triazine as a Purine Bioisostere: Access to Potent Cyclin-Dependent Kinase Inhibitor (R)-Roscovitine Analogue

    JOURNAL OF MEDICINAL CHEMISTRY . 52(3): 655-663. Nº de cites: 78

    [doi:10.1021/jm801340z]

  • Bettayeb K, Tirado OM, Marionneau-Lambot S, Ferandin Y, Lozach O, Morris JC, Mateo-Lozano S, Drueckes P, Schächtele C, Kubbutat MH, Liger F, Marquet B, Joseph B, Echalier A, Endicott JA, Notario V and Meijer L.

    Meriolins, a new class of cell death-inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases

    CANCER RESEARCH . 67(17): 8325-8334. Nº de cites: 111

    [doi:10.1158/0008-5472.CAN-07-1826]

  • Mateo-Lozano S, Gokhale PC, Soldatenkov VA, Dritschilo A, Tirado OM and Notario V.

    Combined transcriptional and translational targeting of EWS/FLI-1 in Ewing's sarcoma

    CLINICAL CANCER RESEARCH . 12(22): 6781-6790. Nº de cites: 49

    [doi:10.1158/1078-0432.CCR-06-0609]

  • Tirado OM, Mateo-Lozano S, Villar J, Dettin LE, Llort A, Gallego S, Ban J, Kovar H and Notario V.

    Caveolin-1 (CAV1) is a target of EWS/FLI-1 and a key determinant of the oncogenic phenotype and tumorigenicity of Ewing's sarcoma cells.

    CANCER RESEARCH . 66(20): 9937-9947. Nº de cites: 113

    [doi:10.1158/0008-5472.CAN-06-0927]

  • Tirado OM, Mateo-Lozano S and Notario V.

    Roscovitine is an effective inducer of apoptosis of Ewing's sarcoma family tumor cells in vitro and in vivo

    CANCER RESEARCH . 65(20): 9320-9327. Nº de cites: 56

    [doi:10.1158/0008-5472.CAN-05-1276]

  • Tirado OM, Mateo-Lozano S and Notario V.

    Rapamycin induces apoptosis of JN-DSRCT-1 cells by increasing the Bax: Bcl-xL ratio through concurrent mechanisms dependent and independent of its mTOR inhibitory activity

    Oncogene . 24(20): 3348-3357. Nº de cites: 67

    [doi:10.1038/sj.onc.1208471]

  • Mateo-Lozano S, Tirado OM and Notario V.

    Rapamycin induces the fusion-type independent downregulation of the EWS/FLI-1 proteins and inhibits Ewing's sarcoma cell proliferation

    Oncogene . 22(58): 9282-9287. Nº de cites: 96

    [doi:10.1038/sj.onc.1207081]