Description
The call is launched by EP PerMed (European Partnership for Personalised Medicine), co‑funded by the European Union under Horizon Europe, aiming to support multinational, innovative research projects in personalised medicine (PM) for cardiovascular, metabolic and kidney diseases. The call seeks proposals that develop or validate personalised therapeutic approaches, stratify molecular markers or diagnostics for risk prediction or treatment monitoring, and tailor interventions to patient-specific factors (e.g. multi‑omics data, imaging, digital health, AI, patient‑reported outcomes). Projects may focus on a single disease or explore combinations of cardiovascular, metabolic and kidney conditions, and they must include a strategy for translation into clinical practice (e.g. implementation research, patient outcome, cost/reimbursement, education, ethical/legal/social aspects). The call follows a two‑stage scheme (pre‑proposal and full proposal).

Objectives
To fund multidisciplinary, cross‑sector research consortia that push forward personalised medicine strategies for cardiovascular, metabolic, and kidney diseases - including novel therapies, diagnostics, stratification tools, and translational implementation of patient‑centred interventions.

Buget

Total available budget for the call: approximately € 38 million.
No global per‑project cap is specified in the main text; funding amounts per national/regional funder depend on national regulations. Additional national budget ceilings may apply (e.g. for Poland some caps are defined).

Eligibility / Requirements

• Eligible applicants/partners include:

  • Academic institutions or research institutes.

  • Clinical/public-health institutions (hospitals, healthcare organisations - including clinicians, pharmacists, general practitioners).

  • Private for-profit organisations (e.g., SMEs) or non-profit organisations (foundations, NGOs).

• Consortia must be transnational, with at least three partners from three different EU Member States or Associated Countries, each requesting funding from their national/regional funder.

• Independent legal entities only; the coordinator must be eligible for national funding.

• Maximum two partners per country requesting funding from the same funder.

• Patient or citizen organisations may be included as additional partners (funding on own or if eligible).

• Pre-proposal stage: up to 6 partners (7 in defined cases); Full proposal stage: up to 7-8 partners if including underrepresented regions ("widening" option).

• Projects may last up to 3 years.

• Inclusion of an early-career researcher (ECR) as PI is strongly recommended.

• Additional country-specific eligibility rules and national addenda may apply.

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