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  • Mack SC, Pajtler KW, Chavez L, Okonechnikov K, Bertrand KC, Wang X, Erkek S, Federation A, Song A, Lee C, Wang X, McDonald L, Morrow JJ, Saiakhova A, Sin-Chan P, Wu Q, Michaelraj KA, Miller TE, Hubert CG, Ryzhova M, Garzia L, Donovan L, Dombrowski S, Factor DC, Luu B, Valentim CLL, Gimple RC, Morton A, Kim L, Prager BC, Lee JJY, Wu X, Zuccaro J, Thompson Y, Holgado BL, Reimand J, Ke SQ, Tropper A, Lai S, Vijayarajah S, Doan S, Mahadev V, Minan AF, Grobner SN, Lienhard M, Zapatka M, Huang Z, Aldape KD, Carcaboso AM, Houghton PJ, Keir ST, Milde T, Witt H, Li Y, Li CJ, Bian XW, Jones DTW, Scott I, Singh SK, Huang A, Dirks PB, Bouffet E, Bradner JE, Ramaswamy V, Jabado N, Rutka JT, Northcott PA, Lupien M, Lichter P, Korshunov A, Scacheri PC, Pfister SM, Kool M, Taylor MD and Rich JN.

    Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling

    Nature . 553(7686): 101-105. Number of citations: 158

    [doi:10.1038/nature25169]

  • Chheda ZS, Kohanbash G, Okada K, Jahan N, Sidney J, Pecoraro M, Yang X, Carrera DA, Downey KM, Shrivastav S, Liu S, Lin Y, Lagisetti C, Chuntova P, Watchmaker PB, Mueller S, Pollack IF, Rajalingam R, Carcaboso AM, Mann M, Sette A, Garcia KC, Hou Y and Okada H.

    Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy

    JOURNAL OF EXPERIMENTAL MEDICINE . 215(1): 141-157. Number of citations: 171

    [doi:10.1084/jem.20171046]

  • Pascual-Pastó G, Gene-Olaciregui N, Opezzo JAW, Castillo-Ecija H, Cuadrado-Vilanova M, Paco-Mercader S, Rivero EM, Vilà-Ubach M, Restrepo-Perdomo CA, Torrebadell-Burriel M, Suñol M, Schaquevich P, Mora J, Bramuglia GF, Chantada G and Carcaboso AM.

    Increased delivery of chemotherapy to the vitreous by inhibition of the blood-retinal barrier

    JOURNAL OF CONTROLLED RELEASE . 264: 34-44. Number of citations: 11

    [doi:10.1016/j.jconrel.2017.08.018]

  • Mackay A, Burford A, Carvalho D, Izquierdo E, Fazal-Salom J, Taylor KR, Bjerke L, Clarke M, Vinci M, Nandhabalan M, Temelso S, Popov S, Molinari V, Raman P, Waanders AJ, Han HJ, Gupta S, Marshall L, Zacharoulis S, Vaidya S, Mandeville HC, Bridges LR, Martin AJ, Al-Sarraj S, Chandler C, Ng HK, Li X, Mu K, Trabelsi S, Brahim DH, Kisljakov AN, Konovalov DM, Moore AS, Carcaboso AM, Suñol M, de Torres C, Cruz-Martínez O, Mora J, Shats LI, Stavale JN, Bidinotto LT, Reis RM, Entz-Werle N, Farrell M, Cryan J, Crimmins D, Caird J, Pears J, Monje M, Debily MA, Castel D, Grill J, Hawkins C, Nikbakht H, Jabado N, Baker SJ, Pfister SM, Jones DTW, Fouladi M, von Bueren AO, Baudis M, Resnick A and Jones C.

    Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma

    Cancer Cell . 32(4): 520-537. Number of citations: 643

    [doi:10.1016/j.ccell.2017.08.017]

  • Boeva V, Louis-Brennetot C, Peltier A, Durand S, Pierre-Eugène C, Raynal V, Etchevers HC, Thomas S, Lermine A, Daudigeos-Dubus E, Geoerger B, Orth MF, Grünewald TGP, Diaz E, Ducos B, Surdez D, Carcaboso AM, Medvedeva I, Deller T, Combaret V, Lapouble E, Pierron G, Grossetête-Lalami S, Baulande S, Schleiermacher G, Barillot E, Rohrer H, Delattre O and Janoueix-Lerosey I.

    Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries

    NATURE GENETICS . 49(9): 1408-1413. Number of citations: 278

    [doi:10.1038/ng.3921]

  • Cockle JV, Brüning-Richardson A, Scott KJ, Thompson J, Kottke T, Morrison E, Ismail A, Carcaboso AM, Rose A, Selby P, Conner J, Picton S, Short S, Vile R, Melcher A and Ilett E.

    Oncolytic Herpes Simplex Virus Inhibits Pediatric Brain Tumor Migration and Invasion

    MOLECULAR THERAPY-ONCOLYTICS . 5: 75-86. Number of citations: 22

    [doi:10.1016/j.omto.2017.04.002]

  • Haque F, Varlet P, Puntonet J, Storer L, Bountali A, Rahman R, Grill J, Carcaboso AM, Jones C, Layfield R and Grundy RG.

    Evaluation of a novel antibody to define histone 3.3 G34R mutant brain tumours

    Acta neuropathologica communications . 5: 45-45. Number of citations: 28

    [doi:10.1186/s40478-017-0449-1]

  • Sewing AC, Lagerweij T, van Vuurden DG, Meel MH, Veringa SJ, Carcaboso AM, Gaillard PJ, Peter Vandertop W, Wesseling P, Noske D, Kaspers GJ and Hulleman E.

    Preclinical evaluation of convection-enhanced delivery of liposomal doxorubicin to treat pediatric diffuse intrinsic pontine glioma and thalamic high-grade glioma

    JOURNAL OF NEUROSURGERY-PEDIATRICS . 19(5): 518-530. Number of citations: 23

    [doi:10.3171/2016.9.PEDS16152]

  • Mohammad F, Weissmann S, Leblanc B, Pandey DP, Højfeldt JW, Comet I, Zheng C, Johansen JV, Rapin N, Porse BT, Tvardovskiy A, Jensen ON, Gene-Olaciregui N, Lavarino C, Suñol M, de Torres C, Mora J, Carcaboso AM and Helin K.

    EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas

    NATURE MEDICINE . 23(4): 483-492. Number of citations: 385

    [doi:10.1038/nm.4293]

  • Monterrubio C, Paco-Mercader S, Gene-Olaciregui N, Pascual-Pastó G, Vilà-Ubach M, Cuadrado-Vilanova M, Ferrandiz MM, Castillo-Ecija H, Glisoni R, Kuplennik N, Jungbluth A, de Torres C, Lavarino C, Cheung NV, Mora J, Sosnik A and Carcaboso AM.

    Targeted drug distribution in tumor extracellular fluid of GD2-expressing neuroblastoma patient-derived xenografts using SN-38-loaded nanoparticles conjugated to the monoclonal antibody 3F8

    JOURNAL OF CONTROLLED RELEASE . 255: 108-119. Number of citations: 33

    [doi:10.1016/j.jconrel.2017.04.016]