Laia Alsina Manrique de Lara
Jefe de Grupo
Research group
Researcher Laia Alsina graduated in Medicine in 2000 from the University of Barcelona, and he obtained a specialization in Paediatrics in 2004 at the Hospital San Juan de Dios Barcelona. She obtained her PhD degree from the University of Barcelona, in 2008.
Between 2008 and 2010 he completed a postdoctoral stay at the Baylor Institute for Immunology Research in Dallas, where he studied the immune pathways related to primary immunodeficiencies.
In 2018, she was appointed Head of the Unit of Clinical Immunology and Primary Immunodeficiencies of the SJD Barcelona Children's Hospital and coordinated the Unit of Clinical Immunology between the Clinical Hospital and Sant Joan de Déu.
She is an Associate Professor at the University of Barcelona, since 2018.
She currently co-leads the Study Group of Diseases for Immune Dysfunction in Paediatrics (GEMDIP) where he studies the pathways affected in different forms of primary immunodeficiency, and how to apply this knowledge in personalized therapies in patients with diseases due to immune dysfunction, as well as the impact on the childhood immune system of various immunosuppressive therapies.
Professional network profiles
Related websites
SJD Barcelona Children's Hospital Last Publications
- Utpatel C, Zavaleta M, Rojas-Bolivar D, Mühlbach A, Picoy J, Portugal W, Esteve-Solé A, Alsina L, Miotto P, Bartholomeu DC, Sanchez J, Cuadros DF, Alarcon JO, Niemann S and Huaman MA Prison as a driver of recent transmissions of multidrug-resistant tuberculosis in Callao, Peru: a cross-sectional study. LANCET REGIONAL HEALTH-AMERICAS . 31: 100674-100674.
- Staniek J, Kalina T, Andrieux G, Boerries M, Janowska I, Fuentes M, Díez P, Bakardjieva M, Stancikova J, Raabe J, Neumann J, Schwenk S, Arpesella L, Stuchly J, Benes V, García Valiente R, Fernández García J, Carsetti R, Piano Mortari E, Català-Temprano A, de la Calle O, Sogkas G, Neven B, Rieux-Laucat F, Magerus A, Neth O, Olbrich P, Voll RE, Alsina L, Allende LM, Gonzalez-Granado LI, Böhler C, Thiel J, Venhoff N, Lorenzetti R, Warnatz K, Unger S, Seidl M, Mielenz D, Schneider P, Ehl S, Rensing-Ehl A, Smulski CR and Rizzi M Non-apoptotic FAS signaling controls mTOR activation and extrafollicular maturation in human B cells Science immunology . 9(91): .
- Kennedy-Batalla R, Acevedo D, Luo Y, Esteve-Solé A, Vlagea A, Correa-Rocha R, Seoane-Reula ME and Alsina L Treg in inborn errors of immunity: gaps, knowns and future perspectives FRONTIERS IN IMMUNOLOGY . 14: 1278759-1278759.
Projects
- Project name:
- Plataforma de Biobanco, Biomodelos e Impresión 3D Sant Joan de Déu como paradigma de excelencia en investigacion Pediatrica.
- Leader
- Cristina Jou Muñoz
- Funding entities:
- Instituto de Salud Carlos III (ISCIII)
- Code
- PT23/00002
- Starting - finishing date:
- 2024 - 2026
- Project name:
- Functional profiling array for primary immune regulatory disorders-research
- Leader
- Laia Alsina Manrique de Lara
- Funding entities:
- Pharming Group N.V.
- Code
- PCP00389
- Starting - finishing date:
- 2023 - 2025
- Project name:
- Caracterització funcional de les cèl·lules T reguladores i vies immunes relacionades mitjançant òmiques, en pacients pediàtrics amb errors congènits de la immunitat i desregulació immune, per al desenvolupament de teràpies dirigides
- Leader
- Laia Alsina Manrique de Lara
- Funding entities:
- Hospital Sant Joan de Déu - Esplugues HSJD
- Code
- BR202101
- Starting - finishing date:
- 2022 - 2025
News
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Mutation in DOCK11 gene explains rare disorder in immune system regulation
Researchers from the Institut de Recerca Sant Joan de Déu - SJD Barcelona Children's Hospital participate in an international study, published in the prestigious scientific journal New England Journal of Medicine, which describes for the first time a new disease of the immune system caused by a mutation of the DOCK11 gene.
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Researchers discover a key factor that predicts COVID-19 disease severity
A study led by Drs. Laia Alsina and Iolanda Jordan from the IRSJD evidences a key factor that predicts the severity of COVID-19: an alteration of the first immune response to SARS-CoV-2 infection, in key molecules in the anti-infective response. The study has been published in open access in the journal iScience.
More activities
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Defensa tesi doctoral: Yiyi Luo
Aula 14 (Facultat Medicina · UB) and online
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Defensa tesi doctoral: Ana Pilar García García
Auditori Plaza, Hospital Sant Joan de Déu · Online